Ontology highlight
ABSTRACT:
SUBMITTER: Durand NC
PROVIDER: S-EPMC5846465 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Durand Neva C NC Shamim Muhammad S MS Machol Ido I Rao Suhas S P SS Huntley Miriam H MH Lander Eric S ES Aiden Erez Lieberman EL
Cell systems 20160701 1
Hi-C experiments explore the 3D structure of the genome, generating terabases of data to create high-resolution contact maps. Here, we introduce Juicer, an open-source tool for analyzing terabase-scale Hi-C datasets. Juicer allows users without a computational background to transform raw sequence data into normalized contact maps with one click. Juicer produces a hic file containing compressed contact matrices at many resolutions, facilitating visualization and analysis at multiple scales. Struc ...[more]