Ontology highlight
ABSTRACT:
SUBMITTER: Zanchi MM
PROVIDER: S-EPMC5598363 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Zanchi Mariane Magalhães MM Manfredini Vanusa V Brum Daniela Dos Santos DDS Vargas Laura Musacchio LM Spiazzi Cristiano Chiapinotto CC Soares Melina Bucco MB Izaguirry Aryele Pinto AP Santos Francielli Weber FW
Toxicology reports 20141231
Green tea presents catechins as its major components and it has a potential antioxidant activity. Cyclophosmamide (CP) is an antineoplastic and immunosuppressive agent, known to reduce fertility. In the present study, we evaluated the effect of green tea infusion on cyclophosphamide-induced damage in male mice reproductive system. Mice received green tea infusion (250 mg/kg) or vehicle by gavage for 14 days. Saline or CP were injected intraperitoneally at a single dose (100 mg/kg) at the 14th da ...[more]