Ontology highlight
ABSTRACT:
SUBMITTER: Durell SR
PROVIDER: S-EPMC5604469 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Durell Stewart R SR Ben-Naim Arieh A
Biopolymers 20170801 8
The process of protein folding is obviously driven by forces exerted on the atoms of the amino-acid chain. These forces arise from interactions with other parts of the protein itself (direct forces), as well as from interactions with the solvent (solvent-induced forces). We present a statistical-mechanical formalism that describes both these direct and indirect, solvent-induced thermodynamic forces on groups of the protein. We focus on 2 kinds of protein groups, commonly referred to as hydrophob ...[more]