Ontology highlight
ABSTRACT:
SUBMITTER: Zhang H
PROVIDER: S-EPMC5605432 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Zhang Huaiying H Aonbangkhen Chanat C Tarasovetc Ekaterina V EV Ballister Edward R ER Chenoweth David M DM Lampson Michael A MA
Nature chemical biology 20170814 10
Kinetochores act as hubs for multiple activities during cell division, including microtubule interactions and spindle checkpoint signaling. Each kinetochore can act autonomously, and activities change rapidly as proteins are recruited to, or removed from, kinetochores. Understanding this dynamic system requires tools that can manipulate kinetochores on biologically relevant temporal and spatial scales. Optogenetic approaches have the potential to provide temporal and spatial control with molecul ...[more]