Ontology highlight
ABSTRACT:
SUBMITTER: Men J
PROVIDER: S-EPMC7324573 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Men Jing J Li Airong A Jerwick Jason J Li Zilong Z Tanzi Rudolph E RE Zhou Chao C
Communications biology 20200629 1
Drosophila is a powerful genetic model system for cardiovascular studies. Recently, optogenetic pacing tools have been developed to control Drosophila heart rhythm noninvasively with blue light, which has a limited penetration depth. Here we developed both a red-light sensitive opsin expressing Drosophila system and an integrated red-light stimulation and optical coherence microscopy (OCM) imaging system. We demonstrated noninvasive control of Drosophila cardiac rhythms using a single light sour ...[more]