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Towards an ultra-rapid smartphone- connected test for infectious diseases.

ABSTRACT: The development is reported of an ultra-rapid, point-of-care diagnostic device which harnesses surface acoustic wave (SAW) biochips, to detect HIV in a finger prick of blood within 10?seconds (sample-in-result-out). The disposable quartz biochip, based on microelectronic components found in every consumer smartphone, is extremely fast because no complex labelling, amplification or wash steps are needed. A pocket-sized control box reads out the SAW signal and displays results electronically. High analytical sensitivity and specificity are found with model and real patient blood samples. The findings presented here open up the potential of consumer electronics to cut lengthy test waiting times, giving patients on the spot access to potentially life-saving treatment and supporting more timely public health interventions to prevent disease transmission.

SUBMITTER: Turbe V

PROVIDER: S-EPMC5607310 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature

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Towards an ultra-rapid smartphone- connected test for infectious diseases.

Turbé Valérian V Gray Eleanor R ER Lawson Victoria E VE Nastouli Eleni E Brookes Jennifer C JC Weiss Robin A RA Pillay Deenan D Emery Vincent C VC Verrips C Theo CT Yatsuda Hiromi H Athey Dale D McKendry Rachel A RA

Scientific reports 20170920 1

The development is reported of an ultra-rapid, point-of-care diagnostic device which harnesses surface acoustic wave (SAW) biochips, to detect HIV in a finger prick of blood within 10 seconds (sample-in-result-out). The disposable quartz biochip, based on microelectronic components found in every consumer smartphone, is extremely fast because no complex labelling, amplification or wash steps are needed. A pocket-sized control box reads out the SAW signal and displays results electronically. High ...[more]

PMID: 28931860

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