Ontology highlight
ABSTRACT:
SUBMITTER: Ai JW
PROVIDER: S-EPMC6758691 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Ai Jing-Wen JW Zhou Xian X Xu Teng T Yang Minling M Chen Yuanyuan Y He Gui-Qing GQ Pan Ningp N Cai Yuwei Y Li Yongjun Y Wang Xiaorui X Su Hang H Wang Ting T Zeng Weiqi W Zhang Wen-Hong WH
Emerging microbes & infections 20190101 1
Rapid and simple-to-use diagnostic methods for tuberculosis are urgently needed. Recent development has unveiled the diagnostic power of the CRISPR system in the detection of viral infections. However, its potential use in detecting the <i>Mycobacterium tuberculosis</i> complex (MTB) remained unexplored. We developed a rapid CRISPR-based assay for TB detection and conducted a retrospective cohort study of 179 patients to evaluate the CRISPR-MTB test for identifying MTB in various forms of direct ...[more]