Ontology highlight
ABSTRACT:
SUBMITTER: Poreba M
PROVIDER: S-EPMC5610424 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Chemical reviews 20151109 22
Caspases are proteases of clan CD and were described for the first time more than two decades ago. They play critical roles in the control of regulated cell death pathways including apoptosis and inflammation. Due to their involvement in the development of various diseases like cancer, neurodegenerative diseases, or autoimmune disorders, caspases have been intensively investigated as potential drug targets, both in academic and industrial laboratories. This review presents a thorough, deep, and ...[more]