Peripheral artery disease and risk of adverse outcomes in heart failure with preserved ejection fraction.

ABSTRACT:

Background

Peripheral artery disease (PAD) in heart failure with preserved ejection fraction (HFpEF) is associated with an increased mortality risk, but the risk of individual outcomes associated with PAD in this patient group is less clear.

Hypothesis

PAD is associated with adverse outcomes in HFpEF, including hospitalization and specific cardiovascular outcomes.

Methods

We examined the association between PAD and adverse outcomes in 3385 patients with HFpEF (mean age, 69 ± 9.6 years; 49% male; 89% white) from the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist Trial (TOPCAT). Baseline PAD was identified by self-reported history and medical-record review. The following outcomes were adjudicated by a clinical endpoint committee: ho

SUBMITTER: Sandesara PB 

PROVIDER: S-EPMC5610588 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature