Retinal imaging in human autopsy eyes using a custom optical coherence tomography periscope.
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ABSTRACT:
SUBMITTER: McNabb RP
PROVIDER: S-EPMC5611930 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Publications
Retinal imaging in human autopsy eyes using a custom optical coherence tomography periscope.
McNabb Ryan P RP Tian James J Farsiu Sina S Izatt Joseph A JA Lad Eleonora M EM Kuo Anthony N AN
Biomedical optics express 20170821 9
Age-related macular degeneration (AMD) is a major cause of vision loss in the elderly. To better study the pathobiology of AMD, postmortem eyes offer an excellent opportunity to correlate optical coherence tomography (OCT) imaging characteristics with histopathology. However, postmortem eyes from autopsy present challenges to standard OCT imaging including opaque anterior segment structures and standard of care autopsy processing resulting in oblique views to the macula. To overcome these challe ...[more]
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