Ontology highlight
ABSTRACT:
SUBMITTER: Orringer DA
PROVIDER: S-EPMC5612414 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Orringer Daniel A DA Pandian Balaji B Niknafs Yashar S YS Hollon Todd C TC Boyle Julianne J Lewis Spencer S Garrard Mia M Hervey-Jumper Shawn L SL Garton Hugh J L HJL Maher Cormac O CO Heth Jason A JA Sagher Oren O Wilkinson D Andrew DA Snuderl Matija M Venneti Sriram S Ramkissoon Shakti H SH McFadden Kathryn A KA Fisher-Hubbard Amanda A Lieberman Andrew P AP Johnson Timothy D TD Xie X Sunney XS Trautman Jay K JK Freudiger Christian W CW Camelo-Piragua Sandra S
Nature biomedical engineering 20170206
Conventional methods for intraoperative histopathologic diagnosis are labour- and time-intensive, and may delay decision-making during brain-tumour surgery. Stimulated Raman scattering (SRS) microscopy, a label-free optical process, has been shown to rapidly detect brain-tumour infiltration in fresh, unprocessed human tissues. Here, we demonstrate the first application of SRS microscopy in the operating room by using a portable fibre-laser-based microscope and unprocessed specimens from 101 neur ...[more]