Ontology highlight
ABSTRACT:
SUBMITTER: Xu B
PROVIDER: S-EPMC5614460 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Tetrahedron 20170125 29
The [1,2]- and [2,3]-rearrangements of iodonium ylides are synthetically useful reactions for the generation of functionalized α-iodoesters. Allylic iodides are coupled with α-diazoesters in the presence of a copper catalyst and a ligand to generate iodonium ylides, which undergo metal-mediated rearrangements. By fine-tuning the structure of the ligand, we have reversed the regioselectivity of copper-catalyzed reactions of iodonium ylides from [2,3]- to [1,2]-rearrangements with the use of alter ...[more]