Ontology highlight
ABSTRACT:
SUBMITTER: Cieslinska A
PROVIDER: S-EPMC5615256 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Cieślińska Anna A Kostyra Elżbieta E Chwała Barbara B Moszyńska-Dumara Małgorzata M Fiedorowicz Ewa E Teodorowicz Małgorzata M Savelkoul Huub F J HFJ
Brain sciences 20170909 9
<h4>Background</h4>Autism spectrum disorder (ASD) is a group of heterogeneous, behaviorally defined disorders whereby currently no biological markers are common to all affected individuals. A deregulated immune response may be contributing to the etiology of ASD. The active metabolite of vitamin D₃ has an immunoregulatory role mediated by binding to the vitamin D receptor (VDR) in monocyte, macrophages, and lymphocytes. The effects of vitamin D and interaction with the VDR may be influenced by p ...[more]