Ontology highlight
ABSTRACT:
SUBMITTER: Mohamedali KA
PROVIDER: S-EPMC5618300 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Mohamedali Khalid A KA Rosenblum Michael G MG
Biomedicines 20170717 3
Angiogenesis is a critical process in numerous diseases, and intervention in neovascularization has therapeutic value in several disease settings, including ocular diseases, arthritis, and in tumor progression and metastatic spread. Various vascular targeting agents have been developed, including those that inhibit growth factor receptor tyrosine kinases, blocking antibodies that interfere with receptor signal transduction, and strategies that trap growth factor ligands. Limited anti-tumor effic ...[more]