Ontology highlight
ABSTRACT:
SUBMITTER: Chatterjee S
PROVIDER: S-EPMC5618627 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20170915 9
Heat shock proteins (HSPs) are a large family of chaperones that are involved in protein folding and maturation of a variety of "client" proteins protecting them from degradation, oxidative stress, hypoxia, and thermal stress. Hence, they are significant regulators of cellular proliferation, differentiation and strongly implicated in the molecular orchestration of cancer development and progression as many of their clients are well established oncoproteins in multiple tumor types. Interestingly, ...[more]