Ontology highlight
ABSTRACT:
SUBMITTER: Jourd'heuil FL
PROVIDER: S-EPMC5620122 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Jourd'heuil Frances L FL Xu Haiyan H Reilly Timothy T McKellar Keneta K El Alaoui Chaymae C Steppich Julia J Liu Yong Feng YF Zhao Wen W Ginnan Roman R Conti David D Lopez-Soler Reynold R Asif Arif A Keller Rebecca K RK Schwarz John J JJ Thanh Thuy Le Thi LT Kawada Norifumi N Long Xiaochun X Singer Harold A HA Jourd'heuil David D
Arteriosclerosis, thrombosis, and vascular biology 20170810 10
<h4>Objective</h4>The role of hemoglobin and myoglobin in the cardiovascular system is well established, yet other globins in this context are poorly characterized. Here, we examined the expression and function of cytoglobin (CYGB) during vascular injury.<h4>Approach and results</h4>We characterized CYGB content in intact vessels and primary vascular smooth muscle (VSM) cells and used 2 different vascular injury models to examine the functional significance of CYGB in vivo. We found that CYGB wa ...[more]