Ontology highlight
ABSTRACT:
SUBMITTER: Tang R
PROVIDER: S-EPMC6663079 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Tang Rui R Mei Xiaohan X Wang Yung-Chun YC Cui Xiao-Bing XB Zhang Gui G Li Wenjing W Chen Shi-You SY
Biochimica et biophysica acta. Molecular basis of disease 20190602 9
Vascular remodeling is a pathological process following cardiovascular intervention. Vascular smooth muscle cells (VSMC) play a critical role in the vascular remodeling. Long noncoding RNAs (lncRNA) are a class of gene regulators functioning through various mechanisms in physiological and pathological conditions. By using cultured VSMC and rat carotid artery balloon injury model, we found that lncRNA growth arrest specific 5 (GAS5) serves as a negative regulator for VSMC survival in vascular rem ...[more]