Evidence for a Large-Scale Brain System Supporting Allostasis and Interoception in Humans.
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ABSTRACT:
SUBMITTER: Kleckner IR
PROVIDER: S-EPMC5624222 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Evidence for a Large-Scale Brain System Supporting Allostasis and Interoception in Humans.
Kleckner Ian R IR Zhang Jiahe J Touroutoglou Alexandra A Chanes Lorena L Xia Chenjie C Simmons W Kyle WK Quigley Karen S KS Dickerson Bradford C BC Barrett Lisa Feldman LF
Nature human behaviour 20170424
Large-scale intrinsic brain systems have been identified for exteroceptive senses (e.g., sight, hearing, touch). We introduce an analogous system for representing sensations from within the body, called interoception, and demonstrate its relation to regulating peripheral systems in the body, called allostasis. Employing the recently introduced Embodied Predictive Interoception Coding (EPIC) model, we used tract-tracing studies of macaque monkeys, followed by two intrinsic functional magnetic res ...[more]
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