Ontology highlight
ABSTRACT:
SUBMITTER: Pang C
PROVIDER: S-EPMC5633544 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Pang Chi C Huang Gang G Luo Kaili K Dong Yuying Y He Fengtian F Du Guankui G Xiao Man M Cai Wangwei W
Cancer medicine 20170921 10
miR-206 plays an important role in regulating the growth of multiple cancer cells. Cyclin-dependent kinase 9 (CDK9) stimulates the production of abundant prosurvival proteins, leading to impaired apoptosis of cancer cells. However, it is unknown whether CDK9 is involved in the miR-206-mediated growth suppression of hepatocellular carcinoma (HCC) cells. In this study, we found that the expression level of miR-206 was significantly lower in HCC cell lines than that in normal hepatic cell line (L02 ...[more]