Ontology highlight
ABSTRACT:
SUBMITTER: Wang GF
PROVIDER: S-EPMC5638971 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Wang Gui-Fang GF Ji Qing-Shan QS Qi Bing B Yu Guo-Cheng GC Liu Lian L Zhong Jing-Xiang JX
International journal of ophthalmology 20171018 10
<h4>Aim</h4>To investigate the correlation between lumican (LUM) gene and high myopia in a Southern Chinese population.<h4>Methods</h4>The study comprised of 95 high myopia patients with a spherical equivalent ≤-6.5 diopters (D). The control group recruited 95 individuals with a spherical equivalent ranging from -0.5 D to +0.5 D. Direct sequencing was used to detect the single nucleotide polymorphisms (SNPs) of LUM gene in coding region. Genotype distributions were tested for Hardy-Weinberg dise ...[more]