Recurrent wheeze and its relationship with lung function and airway inflammation in preschool children: a cross-sectional study in South Korea.

ABSTRACT:

Background

Relationship between recurrent wheeze and airway function and inflammation in preschool children is not fully known.

Objective

To investigate the relationship between recurrent wheeze and airway inflammation, lung function, airway hyper-reactivity (AHR) and atopy in preschool children.

Design

Observational study, comparing forced expiratory volume in 1 s (FEV₁), forced vital capacity (FVC) and mid-forced expiratory flow (FEF_25%-75%), dose-response slope (DRS), exhaled nitric oxide (eNO) and atopic sensitisation between children with recurrent wheeze and those without.

Setting

Population-based, cross-sectional study in Seoul and the Gyeonggi province of Korea conducted as a government-funded programme to perform standardised meas

SUBMITTER: Soh JE 

PROVIDER: S-EPMC5640071 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature