Ontology highlight
ABSTRACT:
SUBMITTER: Manageiro V
PROVIDER: S-EPMC5640717 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Manageiro Vera V Félix David D Jones-Dias Daniela D Sampaio Daniel A DA Vieira Luís L Sancho Luísa L Ferreira Eugénia E Caniça Manuela M
Frontiers in microbiology 20171009
A new QepA4 variant was detected in an O86:H28 ST156-<i>fimH38 Escherichia coli</i>, showing a multidrug-resistance phenotype. PAβN inhibition of <i>qepA4-</i>harboring transconjugant resulted in increase of nalidixic acid accumulation. The <i>qepA4</i> and <i>catA1</i> genes were clustered in a 26.0-kp contig matching an IncF-type plasmid, and containing a Tn21-type transposon with multiple mobile genetic elements. This QepA variant is worrisome because these determinants might facilitate the s ...[more]