Ontology highlight
ABSTRACT:
SUBMITTER: Wu AJ
PROVIDER: S-EPMC5643234 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Wu Abraham J AJ Gillis Andrea A Foster Amanda A Woo Kaitlin K Zhang Zhigang Z Gelblum Daphna Y DY Downey Robert J RJ Rosenzweig Kenneth E KE Ong Leonard L Perez Carmen A CA Pietanza M Catherine MC Krug Lee L Rudin Charles M CM Rimner Andreas A
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20170801 1
<h4>Background and purpose</h4>The relationship between tumor-node-metastasis (TNM) stage and patterns of failure in limited-stage small cell lung cancer (LS-SCLC) remains unclear. We hypothesized that TNM stage predicts brain metastasis risk, and could inform the use of prophylactic cranial irradiation.<h4>Material and methods</h4>We reviewed 283 patients with stage I-IIIB SCLC. Competing-risks regression was used to analyze local, distant, and brain failure. Multivariate analysis was used to e ...[more]