Ontology highlight
ABSTRACT:
SUBMITTER: Wu S
PROVIDER: S-EPMC5645731 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Chemical science 20150205 4
A Rh(iii) catalyzed formal [4 + 2 + 2] cyclization of <i>N</i>-pivaloyloxybenzamides <b>1</b> with 1,6-allene-enes <b>2</b> by C-H functionalization is reported. The reactions occur at room temperature and are compatible with air and moisture with a tolerance of many synthetically useful functional groups. The follow-up modifications of the products have been demonstrated. After careful mechanistic studies and DFT calculation, a reaction mechanism was proposed. ...[more]