Ontology highlight
ABSTRACT:
SUBMITTER: Wesolowski R
PROVIDER: S-EPMC5647220 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Wesolowski Robert R Duggan Megan C MC Stiff Andrew A Markowitz Joseph J Trikha Prashant P Levine Kala M KM Schoenfield Lynn L Abdel-Rasoul Mahmoud M Layman Rachel R Ramaswamy Bhuvaneswari B Macrae Erin R ER Lustberg Maryam B MB Reinbolt Raquel E RE Mrozek Ewa E Byrd John C JC Caligiuri Michael A MA Mace Thomas A TA Carson William E WE
Cancer immunology, immunotherapy : CII 20170707 11
This study sought to evaluate whether myeloid-derived suppressor cells (MDSC) could be affected by chemotherapy and correlate with pathologic complete response (pCR) in breast cancer patients receiving neo-adjuvant chemotherapy. Peripheral blood levels of granulocytic (G-MDSC) and monocytic (M-MDSC) MDSC were measured by flow cytometry prior to cycle 1 and 2 of doxorubicin and cyclophosphamide and 1st and last administration of paclitaxel or paclitaxel/anti-HER2 therapy. Of 24 patients, 11, 6 an ...[more]