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A mechanosensitive Ca²⁺ channel activity is dependent on the developmental regulator DEK1.

ABSTRACT: Responses of cells to mechanical stress are thought to be critical in coordinating growth and development. Consistent with this idea, mechanically activated channels play important roles in animal development. For example, the PIEZO1 channel controls cell division and epithelial-layer integrity and is necessary for vascular development in mammals. In plants, the actual contribution of mechanoperception to development remains questionable because very few putative mechanosensors have been identified and the phenotypes of the corresponding mutants are rather mild. Here, we show that the Arabidopsis Defective Kernel 1 (DEK1) protein, which is essential for development beyond early embryogenesis, is associated with a mechanically activated Ca²⁺ current in planta, suggesting that perception of mechanical stress plays a critical role in plant development.

SUBMITTER: Tran D

PROVIDER: S-EPMC5647327 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature

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A mechanosensitive Ca2+ channel activity is dependent on the developmental regulator DEK1.

Tran Daniel D Galletti Roberta R Neumann Enrique D ED Dubois Annick A Sharif-Naeini Reza R Geitmann Anja A Frachisse Jean-Marie JM Hamant Olivier O Ingram Gwyneth C GC

Nature communications 20171018 1

Responses of cells to mechanical stress are thought to be critical in coordinating growth and development. Consistent with this idea, mechanically activated channels play important roles in animal development. For example, the PIEZO1 channel controls cell division and epithelial-layer integrity and is necessary for vascular development in mammals. In plants, the actual contribution of mechanoperception to development remains questionable because very few putative mechanosensors have been identif ...[more]

PMID: 29044106

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