Ontology highlight
ABSTRACT:
SUBMITTER: Perez-Schindler J
PROVIDER: S-EPMC5647435 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Pérez-Schindler Joaquín J Kanhere Aditi A Edwards Lindsay L Allwood J William JW Dunn Warwick B WB Schenk Simon S Philp Andrew A
Scientific reports 20171018 1
Enhanced coverage and sensitivity of next-generation 'omic' platforms has allowed the characterization of gene, metabolite and protein responses in highly metabolic tissues, such as, skeletal muscle. A limitation, however, is the capability to determine interaction between dynamic biological networks. To address this limitation, we applied Weighted Analyte Correlation Network Analysis (WACNA) to RNA-seq and metabolomic datasets to identify correlated subnetworks of transcripts and metabolites in ...[more]