Probing Cell Adhesion Profiles with a Microscale Adhesive Choice Assay.
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ABSTRACT:
SUBMITTER: Kittur H
PROVIDER: S-EPMC5647542 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Publications
Probing Cell Adhesion Profiles with a Microscale Adhesive Choice Assay.
Kittur Harsha H Tay Andy A Hua Avery A Yu Min M Di Carlo Dino D
Biophysical journal 20171001 8
In this work, we introduce, to our knowledge, a new set of adhesion-based biomarkers for characterizing mammalian cells. Mammalian cell adhesion to the extracellular matrix influences numerous physiological processes. Current in vitro methods to probe adhesion focus on adhesive force to a single surface, which can investigate only a subcomponent of the adhesive, motility, and polarization cues responsible for adhesion in the 3D tissue environment. Here, we demonstrate a method to quantify the tr ...[more]
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