Ontology highlight
ABSTRACT:
SUBMITTER: Weiss ID
PROVIDER: S-EPMC5650270 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Weiss Ido D ID Huff Lyn M LM Evbuomwan Moses O MO Xu Xin X Dang Hong Duc HD Velez Daniel S DS Singh Satya P SP Zhang Hongwei H HH Gardina Paul J PJ Lee Jae-Ho JH Lindenberg Liza L Myers Timothy G TG Paik Chang H CH Schrump David S DS Pittaluga Stefania S Choyke Peter L PL Fojo Tito T Farber Joshua M JM
Oncotarget 20170804 43
Expression of the chemokine receptor CXCR4 by many cancers correlates with aggressive clinical behavior. As part of the initial studies in a project whose goal was to quantify CXCR4 expression on cancers non-invasively, we examined CXCR4 expression in cancer samples by immunohistochemistry using a validated anti-CXCR4 antibody. Among solid tumors, we found expression of CXCR4 on significant percentages of major types of kidney, lung, and pancreatic adenocarcinomas, and, notably, on metastases of ...[more]