Ontology highlight
ABSTRACT:
SUBMITTER: Dietz S
PROVIDER: S-EPMC5650322 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Dietz Steffen S Sültmann Holger H Du YueJun Y Reisinger Eva E Riediger Anja Lisa AL Volckmar Anna-Lena AL Stenzinger Albrecht A Schlesner Matthias M Jäger Dirk D Hohenfellner Markus M Duensing Stefan S Grüllich Carsten C Pahernik Sascha S
Oncotarget 20170523 43
The availability of tyrosine kinase inhibitors (TKI) during the past ten years has led to improved response and overall survival of patients suffering from metastatic clear cell renal cell carcinoma (ccRCC). However, most of these tumors will eventually progress due to resistance evolving under therapy. The objective of this pilot study was to determine whether molecular alterations in ccRCC tissues sampled over the course of the disease might be suggestive of potential therapies. We performed w ...[more]