Occupational styrene exposure and acquired dyschromatopsia: A systematic review and meta-analysis.

ABSTRACT:

Background

Styrene is a chemical used in the manufacture of plastic-based products worldwide. We systematically reviewed eligible studies of occupational styrene-induced dyschromatopsia, qualitatively synthesizing their findings and estimating the exposure effect through meta-analysis.

Methods

PubMed, EMBASE, and Web of Science databases were queried for eligible studies. Using a random effects model, we compared measures of dyschromatopsia between exposed and non-exposed workers to calculate the standardized mean difference (Hedges'g). We also assessed between-study heterogeneity and publication bias.

Results

Styrene-exposed subjects demonstrated poorer color vision than did the non-exposed (Hedges' g = 0.56; 95%CI: 0.37, 0.76; P < 0.0001). A non-significant Cochran'

SUBMITTER: Choi AR 

PROVIDER: S-EPMC5652067 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature