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Occupational styrene exposure and acquired dyschromatopsia: A systematic review and meta-analysis.


ABSTRACT: BACKGROUND:Styrene is a chemical used in the manufacture of plastic-based products worldwide. We systematically reviewed eligible studies of occupational styrene-induced dyschromatopsia, qualitatively synthesizing their findings and estimating the exposure effect through meta-analysis. METHODS:PubMed, EMBASE, and Web of Science databases were queried for eligible studies. Using a random effects model, we compared measures of dyschromatopsia between exposed and non-exposed workers to calculate the standardized mean difference (Hedges'g). We also assessed between-study heterogeneity and publication bias. RESULTS:Styrene-exposed subjects demonstrated poorer color vision than did the non-exposed (Hedges' g?=?0.56; 95%CI: 0.37, 0.76; P?

SUBMITTER: Choi AR 

PROVIDER: S-EPMC5652067 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature

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Occupational styrene exposure and acquired dyschromatopsia: A systematic review and meta-analysis.

Choi Ariel R AR   Braun Joseph M JM   Papandonatos George D GD   Greenberg Paul B PB  

American journal of industrial medicine 20170824 11


<h4>Background</h4>Styrene is a chemical used in the manufacture of plastic-based products worldwide. We systematically reviewed eligible studies of occupational styrene-induced dyschromatopsia, qualitatively synthesizing their findings and estimating the exposure effect through meta-analysis.<h4>Methods</h4>PubMed, EMBASE, and Web of Science databases were queried for eligible studies. Using a random effects model, we compared measures of dyschromatopsia between exposed and non-exposed workers  ...[more]

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