Ontology highlight
ABSTRACT:
SUBMITTER: Marzinotto I
PROVIDER: S-EPMC5656581 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Marzinotto Ilaria I Pellegrini Silvia S Brigatti Cristina C Nano Rita R Melzi Raffaella R Mercalli Alessia A Liberati Daniela D Sordi Valeria V Ferrari Maurizio M Falconi Massimo M Doglioni Claudio C Ravassard Philippe P Piemonti Lorenzo L Lampasona Vito V
Scientific reports 20171025 1
miR-204 has been proposed to modulate insulin expression in human pancreatic islets by regulating the expression of the MAFA transcript, and in turn insulin transcription. We investigated miR-204 expression in pancreatic endocrine tumors (PET), a panel of human tissues, tissues derived from pancreatic islet purification, and in induced pluripotent stem cells (iPSCs) differentiated towards a pancreatic endocrine phenotype by quantitative real time RT-PCR or droplet digital PCR (ddPCR). In additio ...[more]