Ontology highlight
ABSTRACT:
SUBMITTER: Woo YM
PROVIDER: S-EPMC5658336 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Woo Yu Mi YM Kim Do Yeon DY Koo Nam Jin NJ Kim Yong-Min YM Lee Sunyoung S Ko Je Yeong JY Shin Yubin Y Kim Bo Hye BH Mun Hyowon H Choi Seonju S Lee Eun Ji EJ Shin Jeong-Oh JO Park Eun Young EY Bok Jinwoong J Park Jong Hoon JH
Scientific reports 20171026 1
Autosomal polycystic kidney disease (ADPKD) is a common inherited renal disease characterized by the development of numerous fluid-filled cysts in both kidneys. We investigated miRNA-mediated regulatory systems and networks that play an important role during cystogenesis through integrative analysis of miRNA- and RNA-seq using two ADPKD mouse models (conditional Pkd1- or Pkd2-deficient mice), at three different time points (P1, P3, and P7). At each time point, we identified 13 differentially exp ...[more]