Ontology highlight
ABSTRACT:
SUBMITTER: English DF
PROVIDER: S-EPMC5659748 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
English Daniel Fine DF McKenzie Sam S Evans Talfan T Kim Kanghwan K Yoon Euisik E Buzsáki György G
Neuron 20171001 2
Excitatory control of inhibitory neurons is poorly understood due to the difficulty of studying synaptic connectivity in vivo. We inferred such connectivity through analysis of spike timing and validated this inference using juxtacellular and optogenetic control of presynaptic spikes in behaving mice. We observed that neighboring CA1 neurons had stronger connections and that superficial pyramidal cells projected more to deep interneurons. Connection probability and strength were skewed, with a m ...[more]