Ontology highlight
ABSTRACT:
SUBMITTER: Kuznetsov NV
PROVIDER: S-EPMC5660450 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Kuznetsov Nikolai V NV Almuzzaini Bader B Kritikou Joanna S JS Baptista Marisa A P MAP Oliveira Mariana M S MMS Keszei Marton M Snapper Scott B SB Percipalle Piergiorgio P Westerberg Lisa S LS
Genome medicine 20171027 1
<h4>Background</h4>The Wiskott-Aldrich syndrome protein (WASp) family of actin-nucleating factors are present in the cytoplasm and in the nucleus. The role of nuclear WASp for T cell development remains incompletely defined.<h4>Methods</h4>We performed WASp chromatin immunoprecipitation and deep sequencing (ChIP-seq) in thymocytes and spleen CD4<sup>+</sup> T cells.<h4>Results</h4>WASp was enriched at genic and intergenic regions and associated with the transcription start sites of protein-codin ...[more]