Advances in the management of HER2-positive early breast cancer.
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ABSTRACT:
SUBMITTER: Baselga J
PROVIDER: S-EPMC5662944 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Publications
Advances in the management of HER2-positive early breast cancer.
Baselga José J Coleman Robert E RE Cortés Javier J Janni Wolfgang W
Critical reviews in oncology/hematology 20171004
While trastuzumab is firmly established as the cornerstone of therapy for both early and advanced breast cancer expressing human epidermal growth factor receptor 2 (HER2), many patients either do not respond to trastuzumab treatment or progress following therapy. Improved understanding of breast cancer biology, particularly the complex signaling interactions managed by the HER family of receptors, have resulted in development of several novel HER2-directed therapies and combinations. This articl ...[more]
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