Ontology highlight
ABSTRACT:
SUBMITTER: Sgheiza V
PROVIDER: S-EPMC5666386 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Sgheiza Valerie V Novick Bethany B Stanton Sarah S Pierce Jeanetta J Kalmeta Breanne B Holmquist Melody Frink MF Grimaldi Kyle K Bren Kara L KL Michel Lea Vacca LV
FEBS open bio 20171012 11
Nontypeable <i>Haemophilus influenzae</i> (NTHi) are Gram-negative pathogens that contribute to a variety of diseases, including acute otitis media and chronic obstructive pulmonary disease. As NTHi have an absolute requirement for heme during aerobic growth, these bacteria have to scavenge heme from their human hosts. These heme sources can range from free heme to heme bound to proteins, such as hemoglobin. To test the impact of heme structural factors on heme acquisition by NTHi, we prepared a ...[more]