Ontology highlight
ABSTRACT:
SUBMITTER: Shigehiro T
PROVIDER: S-EPMC5666455 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Shigehiro Tsukasa T Masuda Junko J Saito Shoki S Khayrani Apriliana C AC Jinno Kazumasa K Seno Akimasa A Vaidyanath Arun A Mizutani Akifumi A Kasai Tomonari T Murakami Hiroshi H Satoh Ayano A Ito Tetsuya T Hamada Hiroki H Seno Yuhki Y Mandai Tadakatsu T Seno Masaharu M
Nanomaterials (Basel, Switzerland) 20170923 10
Taxanes including paclitaxel and docetaxel are effective anticancer agents preferably sufficient for liposomal drug delivery. However, the encapsulation of these drugs with effective amounts into conventional liposomes is difficult due to their high hydrophobicity. Therefore, an effective encapsulation strategy for liposomal taxanes has been eagerly anticipated. In this study, the mixture of polyethoxylated castor oil (Cremophor EL) and ethanol containing phosphate buffered saline termed as CEP ...[more]