Ontology highlight
ABSTRACT:
SUBMITTER: Chen HY
PROVIDER: S-EPMC5666707 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Chen Hsin-Yuan HY Huang Tsui-Chin TC Shieh Tzong-Ming TM Wu Chi-Hao CH Lin Li-Chun LC Hsia Shih-Min SM
International journal of molecular sciences 20170921 10
Ovarian cancer is one of the commonest gynecologic malignancies, which has a poor prognosis for patients at the advanced stage. Isoliquiritigenin (ISL), an active flavonoid component of the licorice plant, previously demonstrated antioxidant, anti-inflammatory, and tumor suppressive effects. In this study, we investigated the antitumor effect of ISL on human ovarian cancer in vitro using the human ovarian cancer cell lines, OVCAR5 and ES-2, as model systems. Our results show that ISL significant ...[more]