Ontology highlight
ABSTRACT:
SUBMITTER: Miller MC
PROVIDER: S-EPMC5666770 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Miller Michelle C MC Mayo Kevin H KH
International journal of molecular sciences 20171002 10
Chemokines are a family of small, highly conserved cytokines that mediate various biological processes, including chemotaxis, hematopoiesis, and angiogenesis, and that function by interacting with cell surface G-Protein Coupled Receptors (GPCRs). Because of their significant involvement in various biological functions and pathologies, chemokines and their receptors have been the focus of therapeutic discovery for clinical intervention. There are several sub-families of chemokines (e.g., CXC, CC, ...[more]