Immunogenomic Classification of Colorectal Cancer and Therapeutic Implications.
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ABSTRACT:
SUBMITTER: Roelands J
PROVIDER: S-EPMC5666908 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Publications
Immunogenomic Classification of Colorectal Cancer and Therapeutic Implications.
Roelands Jessica J Kuppen Peter J K PJK Vermeulen Louis L Maccalli Cristina C Decock Julie J Wang Ena E Marincola Francesco M FM Bedognetti Davide D Hendrickx Wouter W
International journal of molecular sciences 20171024 10
The immune system has a substantial effect on colorectal cancer (CRC) progression. Additionally, the response to immunotherapeutics and conventional treatment options (e.g., chemotherapy, radiotherapy and targeted therapies) is influenced by the immune system. The molecular characterization of colorectal cancer (CRC) has led to the identification of favorable and unfavorable immunological attributes linked to clinical outcome. With the definition of consensus molecular subtypes (CMSs) based on t ...[more]
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