Ontology highlight
ABSTRACT:
SUBMITTER: Pogodaev AA
PROVIDER: S-EPMC5668888 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Pogodaev Aleksandr A AA Wong Albert S Y ASY Huck Wilhelm T S WTS
Journal of the American Chemical Society 20171019 43
Systems chemistry aims to emulate the functional behavior observed in living systems by constructing chemical reaction networks (CRNs) with well-defined dynamic properties. Future expansion of the complexity of these systems would require external control to tune behavior and temporal organization of such CRNs. In this work, we design and implement a photolabile probe, which upon irradiation strengthens the negative feedback loop of a CRN that produces oscillations of trypsin under out-of-equili ...[more]