Ontology highlight
ABSTRACT:
SUBMITTER: Kim J
PROVIDER: S-EPMC5669570 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Kim Jongshin J Kim Yoo Hyung YH Kim Jaeryung J Park Do Young DY Bae Hosung H Lee Da-Hye DH Kim Kyun Hoo KH Hong Seon Pyo SP Jang Seung Pil SP Kubota Yoshiaki Y Kwon Young-Guen YG Lim Dae-Sik DS Koh Gou Young GY
The Journal of clinical investigation 20170814 9
Angiogenesis is a multistep process that requires coordinated migration, proliferation, and junction formation of vascular endothelial cells (ECs) to form new vessel branches in response to growth stimuli. Major intracellular signaling pathways that regulate angiogenesis have been well elucidated, but key transcriptional regulators that mediate these signaling pathways and control EC behaviors are only beginning to be understood. Here, we show that YAP/TAZ, a transcriptional coactivator that act ...[more]