Ontology highlight
ABSTRACT:
SUBMITTER: Baker YR
PROVIDER: S-EPMC5674140 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Baker Y R YR Hodgkinson J T JT Florea B I BI Alza E E Galloway W R J D WRJD Grimm L L Geddis S M SM Overkleeft H S HS Welch M M Spring D R DR
Chemical science 20170829 11
Many bacterial species, including the human pathogen <i>Pseudomonas aeruginosa</i>, employ a mechanism of intercellular communication known as quorum sensing (QS), which is mediated by signalling molecules termed autoinducers. The <i>Pseudomonas</i> Quinolone Signal (PQS) and 2-Heptyl-3<i>H</i>-4-Quinolone (HHQ) are autoinducers in <i>P. aeruginosa</i>, and they are considered important factors in the progress of infections by this clinically relevant organism. Herein, we report the development ...[more]