Ontology highlight
ABSTRACT:
SUBMITTER: Schultz A
PROVIDER: S-EPMC5680186 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Nature communications 20171110 1
Modulation of airway surface liquid (ASL) pH has been proposed as a therapy for cystic fibrosis (CF). However, evidence that ASL pH is reduced in CF is limited and conflicting. The technical challenges associated with measuring ASL pH in vivo have precluded accurate measurements in humans. In order to address this deficiency, ASL pH was measured in vivo in children using a novel luminescent technology integrated with fibre-optic probes. Here we show that ASL pH in children with CF is similar to ...[more]