Ontology highlight
ABSTRACT:
SUBMITTER: Chau K
PROVIDER: S-EPMC5680413 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Chau K K Hennessy A A Makris A A
Journal of human hypertension 20170824 12
Placental growth factor (PlGF) is an increasingly important molecule in the prediction, diagnosis and treatment of pre-eclampsia. It has pro-angiogenic effects on the feto-placental circulation and supports trophoblast growth. Mechanisms by which PlGF expression is regulated continue to be investigated. Low circulating PlGF precedes the manifestation of clinical disease in pre-eclamptic pregnancies and intrauterine growth restriction. This suggests that low PlGF is a marker of abnormal placentat ...[more]