Ontology highlight
ABSTRACT:
SUBMITTER: Getta BM
PROVIDER: S-EPMC5682215 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20170708 11
Mixed phenotype acute leukemia (MPAL) represents a poorly characterized group of acute leukemias that lack an accepted therapeutic approach and are typically associated with poor outcomes. We present our experience of genomic profiling, pretransplantation therapy, and transplantation outcomes for 36 well-characterized pediatric and adult patients with MPAL, defined according to the 2016 World Health Organization leukemia update. A predominance of acute lymphoid leukemia (ALL)-associated mutation ...[more]