Ventral Striatum Connectivity During Reward Anticipation in Adolescent Smokers.
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ABSTRACT:
SUBMITTER: Jollans L
PROVIDER: S-EPMC5684700 | biostudies-literature | 2016 Jan-Mar
REPOSITORIES: biostudies-literature
Publications
Ventral Striatum Connectivity During Reward Anticipation in Adolescent Smokers.
Jollans Lee L Zhipeng Cao C Icke Ilknur I Greene Ciara C Kelly Clare C Banaschewski Tobias T Bokde Arun L W AL Bromberg Uli U Büchel Christian C Cattrell Anna A Conrod Patricia J PJ Desrivières Sylvane S Flor Herta H Frouin Vincent V Gallinat Jürgen J Garavan Hugh H Gowland Penny P Heinz Andreas A Ittermann Bernd B Martinot Jean-Luc JL Artiges Eric E Nees Frauke F Papadopoulos Orfanos Dimitri D Paus Tomáš T Smolka Michael N MN Walter Henrik H Schumann Gunter G Whelan Robert R
Developmental neuropsychology 20160101 1-2
Substance misusers, including adolescent smokers, often have reduced reward system activity during processing of non-drug rewards. Using a psychophysiological interaction approach, we examined functional connectivity with the ventral striatum during reward anticipation in a large (N = 206) sample of adolescent smokers. Increased smoking frequency was associated with (1) increased connectivity with regions involved in saliency and valuation, including the orbitofrontal cortex and (2) reduced conn ...[more]
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