Ontology highlight
ABSTRACT:
SUBMITTER: Jiang P
PROVIDER: S-EPMC5685300 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Jiang Peiyong P Peng Xianlu X Su Xiaoxi X Sun Kun K Yu Stephanie C Y SCY Chu Weng In WI Leung Tak Y TY Sun Hao H Chiu Rossa W K RWK Lo Yuk Ming Dennis YMD Chan Kwan Chee Allen KCA
NPJ genomic medicine 20160511
Noninvasive prenatal testing using massively parallel sequencing of maternal plasma DNA has been rapidly adopted in clinical use worldwide. Fetal DNA fraction in a maternal plasma sample is an important parameter for accurate interpretations of these tests. However, there is a lack of methods involving low-sequencing depth and yet would allow a robust and accurate determination of fetal DNA fraction in maternal plasma for all pregnancies. In this study, we have developed a new method to accurate ...[more]