Ontology highlight
ABSTRACT:
SUBMITTER: Khatchikian CE
PROVIDER: S-EPMC5688016 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Khatchikian Camilo E CE Nadelman Robert B RB Nowakowski John J Schwartz Ira I Wormser Gary P GP Brisson Dustin D
Diagnostic microbiology and infectious disease 20170825 4
Lyme disease, caused by the bacterium Borrelia burgdorferi, is the most common tick-borne infection in the US. Recent studies have demonstrated that the incidence of human Lyme disease would have been even greater were it not for the presence of strain-specific immunity, which protects previously infected patients against subsequent infections by the same B. burgdorferi strain. Here, spatial heterogeneity is incorporated into epidemiological models to accurately estimate the impact of strain-spe ...[more]